Cuckoo sandbox is an automated malware analysis system. Its does utilize virtualization engine to isolate malware execution and analysis. You will be given a web-interface, as well as CLI tools to communicate with cuckoo, such to upload, and reviewing all reports.

I’ve found a complete tutorial on this.

http://advancedmalwareprotection.blogspot.com/2012/03/installing-cuckoo-on-max-os-x-lion.html

Hope this would help anyone to have this. The tutorial is a bit technical. If you’re not familiar with Mac system or Terminal, you might want just to use any public sandbox.